Schleinitz, J.; Chinchilla-Garzon, C.; Perfetto, A.; Escoudé, E.; Makhloutah, A.; Gontard, G.; Vitale, M. R.; Goujon, A.; Felpin, F.-X.; Binet, L.; Ciofini, I.; Hudhomme, P.; Grimaud, L.
Organometallics 2024, X, XXX-XXX, DOI
132- Pure Shift NMR in Continuous Flow
Bazzoni, M.; Régheasse, A.; Caytan, E.; Felpin, F.-X.; Giraudeau, P.; Bernard, A.; Adams, R. W.; Morris, G. A.; Nilsson, M.; Dumez, J. N.
Chem. Eur. J. 2024, X, eXXXXXX, DOI
131- Ultra-Fast and Sustainable Catalyst-Free Chemical Functionalization of Cellulose Paper with Diazo Compounds – Application to Hydrophobic Materials
Calderoni, S.; Bretel, G.; Nongbe, M. C.; Denis, M.; Le Grognec, E.; Felpin, F.-X.
ACS Appl. Polym. Mater. 2024, 6, 7772-7780, DOI
130- Autonomous Reaction Self-Optimization Using In-Line High-Field NMR Spectroscopy
El Sabbagh, N.; Bazzoni, M.; Horbenko, Y.; Bernard, A.; Cortés-Borda, D.; Giraudeau, P.; Felpin, F.-X.; Dumez, J.-N.
React. Chem. Eng. 2024, 9, 2599-2609, DOI
129- Expanding Analytical Horizons: 3D HPLC Calibration Surfaces for Micro-Mole Scale Self-Optimizing Flow Reactor
Vallet, M.; Cortés-Borda, D.; Felpin, F.-X.
React. Chem. Eng. 2024, 9, 2262-2269, DOI
128- A Chemist’s Guide to Multi-Objective Optimization Solvers for Reaction Optimization
127- Enhancing Optimization of Mixed Variables on a Robotic Flow Platform: Integrating Statistical Filtering with Nelder–Mead and Bayesian Methods
Senthil Vel, A.; Konan, K. E.; Cortés-Borda, D.; Felpin, F.-X.
Org. Process Res. Dev. 2024, 28, 1597-1606, DOI
126- Broadband ultrafast 2D NMR spectroscopy for online monitoring in continuous flow
Lhoste, C.; Bazzoni, M.; Bonnet, J.; Bernard, A.; Felpin, F.-X.; Giraudeau, P.; Dumez, J. N.
Analyst, 2023, 148, 5255-5261, DOI
125- Flow Detoxification of a Sulfur Mustard Simulant with Organometallic Compounds Enabled by an Optimization Algorithm
Baptista Da Silva, V.; Mansour, S.; Delaune, A.; Felpin, F.-X., Legros, J.
React. Chem. Eng. 2023, 8, 2658-2663, DOI
124- Ultra-Fast and Sustainable Formal [3 + 3] Cycloadditions Enabled by Mixed Variable Optimization on an Automated Micromole Scale Flow Platform
Konan, K. E.; Senthil Vel, A.; Abollé, A.; Cortés-Borda, D.; Felpin, F.-X.
React. Chem. Eng. 2023, 8, 2446-2454, DOI
123- Signaling Specific Inhibitors of the CB1 Receptor (CB1-SSi) for Cannabis Use Disorder: From Chemical Development to a Randomized Phase 2a Trial
Haney, M.; Vallée, M.; Fabre, S.; Collins Reed, S.; Zanese, M.; Campistron, G.; Arout, C. A.; Foltin, R. W.; Cooper, Z. D.; Kearney-Ramos, T.; Metna, M.; Justinova, Z.; Schindler, C.; Herbert-Chatelain, E.; Bellochio, L.; Cathala, A.; Bari, A.; Serrat, R.; Finlay, D. B.; Caraci, F.; Redon, B.; Martin-Garcia, E.; Busquets-Garcia, A.; Matias, I.; Levin, F. R.; Felpin, F.-X.; Simon, N.; Cota, D.; Spampinato, U.; Maldonado, R.; Shaham, Y.; Glass, M.; Thomsen, L. L.; Mengel, H.; Marsicano, G.; Monlezun, S.; Revest, J.-M.; Piazza, P. V.
Nat. Med. 2023, 29, 1487-1499, DOI
122- In-Line Multidimensional NMR Monitoring of Photochemical Flow Reactions
Bazzoni, M.; Lhoste, C.; Bonnet, J.; Konan, K. E.; Bernard, A.; Giraudeau, P.; Felpin, F.-X.; Dumez, J. N.
Chem. Eur. J. 2023, 29, e202203240, DOI
121- Electrophilic Cyclization of Reticuline-Type Alkloids in Flow via o-Quinol Intermediates
Tra, B. B. J.; Abollé, A.; Lucas, K.; Felpin, F.-X.
J. Flow. Chem. 2023, 13, 257-265, DOI
120- Ultra-Fast Continuous-Flow Photo-Thiol-Ene Functionalization of Conformation-Controled Cinchona Alkaloids
Konan, K. E.; Abollé, A.; Felpin, F.-X.
Eur. J. Org. Chem. 2023, 26, e202201055, DOI
119- Rose Bengal Immobilized on Cellulose Paper for Sustainable Visible-Light Photocatalysis
Nongbe, M. C.; Abollé, A.; Coeffard, V.; Felpin, F.-X.
ChemPlusChem. 2022, 87, e202200242, DOI
118- Analytical Tools Integrated in Continuous Flow Reactors: Which One for What For?
Rodriguez-Zubiri, M.; Felpin, F.-X.
Org. Process. Res. Dev. 2022, 26, 1726-1793, DOI
117- Flow Conditions-Controlled Divergent Oxidative Cyclization of Reticuline-type Alkaloids to Aporphine and Morphinandienone Natural Products
Tra, B. B. J.; Abollé, A.; Coeffard, V. Felpin, F.-X.
Eur. J. Org. Chem. 2022, e202200301, DOI
116- Developing Flow Photo-thiol-ene Functionalization of Conchona Alkaloids with an Autonomous Self-Optimizing Flow Reactor
Kouakou, E. K.; Abollé, A.; Barré, E.; Aka, E. C.; Coeffard, V. Felpin, F.-X.
React. Chem. Eng. 2022, 7, 1346-1357, DOI
115- An investigation of palladium-catalyzed Stille-type cross-coupling of nitroarenes in perylenediimide series
Makhloutah, A.; Hatych, D.; Chartrier, T.; Rocard, L.; Goujon, A.; Felpin, F.-X.; Hudhomme, P.
Org. Biomol. Chem. 2022, 20, 362-365, DOI
114- Development of a continuous flow synthesis of FGIN-1-27 enabled by in-line 19F NMR analyses and optimization algorithms
Vasudevan, N.; Aka, E. C.; Barré, E.; Wimmer, E.; Cortés-Borda, D.; Giraudeau, P.; Farjon, J.; Rodriguez-Zubiri, M.; Felpin, F.-X.
React. Chem. Eng. 2021, 6, 1983-1992, DOI
113- Direct C-H Arylation of Indole-3-Acetic Acid Derivatives Enabled by an Autonomous Self-Optimizing Flow Reactor
Vasudevan, N.; Wimmer, E.; Barré, E.; Cortés-Borda, D.; Rodriguez-Zubiri, M.; Felpin, F.-X.
Adv. Synth. Catal. 2021, 363, 791-799, DOI
112- Ultra-Fast covalent molecular printing on cellulose paper by photo-strain-triggered click ligation – UV LED vs laser irradiations
Denis, M.; Gindre, D.; Felpin, F.-X.
J. Mat. Sci. 2021, 56, 5006-5014, DOI
111- Merging gradient-based methods to improve benchtop NMR spectroscopy: A new tool for flow reaction optimization
Kunjir, S.; Rodriguez-Zubiri, M.; Coeffard, V.; Felpin, F.-X.; Giraudeau, P.; Farjon, J.
ChemPhysChem 2020, 21, 2311-2319, DOI
110- Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles by Continuous Flow: Application to the Synthesis of Valsartan
Carpentier, F.; Felpin, F.-X.; Zammattio, F.; Le Grognec, E.
Org. Process Res. Dev. 2020, 24, 752-761. DOI
109- Comparing Gas-Liquid Segmented and Tube-in-Tube Setups for the Aerobic Dimerization of Desmethoxycarpacine with an Automated Flow Platform
Aka, E. C.; Wimmer, E.; Barré, E.; Cortés-Borda, D.; Ekou, T.; Ekou, L.; Rodriguez-Zubiri, M.; Felpin, F.-X.
Org. Process Res. Dev. 2020, 24, 745-751. DOI
108- Curve fitting complex X-ray photoelectron spectra of graphite-supported copper nanoparticles using informed line shapes
Fernandez, V.; Kiani, D.; Fairley, N.; Felpin, F.-X.; Baltrusaitis, J.
Appl. Surf. Sci. 2020, 505, 143841. DOI
107- Reconfigurable Flow Platform for Automated Reagent Screening and Autonomous Optimization for Bio-inspired Lignans Synthesis
Aka, E. C.; Wimmer, E.; Barré, E.; Vasudevan, N.; Cortés-Borda, D.; Ekou, T.; Ekou, L.; Rodriguez-Zubiri, M.; Felpin, F.-X.
J. Org. Chem. 2019, 84, 14101-14112. DOI
106- Heptylmannose-Functionalized Cellulose for the Binding and Specific Detection of Pathogenic E. coli
Cauwel, M.; Sivignon, A.; Bridot, C.; Nongbe, M. C.; Deniaud, D.; Roubinet, B.; Landemarre, L.; Felpin, F.-X.; Bouckaert, J.; Barnich, N.; Gouin, S.
Chem. Commun. 2019, 55, 10158-10165. DOI
105- A fully bio-sourced adsorbent of heavy metals in water fabricated by immobilization of quinine on cellulose paper
Aka, E. C.; Nongbe, M. C.; Ekou, T.; Ekou, L.; Coeffard, V.; Felpin, F.-X.
J. Environ. Sci. 2019, 84, 174-183. DOI
104- Fabrication of Robust Spatially-Resolved Photochromic Patterns on Cellulose Papers by Covalent Printing for Anti-Counterfeiting Applications
Bretel, G.; Le Grognec, E.; Jacquemin, D.; Hirose, T.; Matsuda, K.; Felpin, F.-X.
ACS Appl. Polym. Mater. 2019, 1, 1240-1250. DOI
103- An Autonomous Self-Optimizing Flow Machine for the Synthesis of Pyridine-Oxazoline (PyOX) ligands
Wimmer, E.; Cortés-Borda, D.; Brochard, S.; Barré, E.; Truchet, C.; Felpin, F.-X
React. Chem. Eng. 2019, 4, 1608-1615. DOI
102- Biaryl Synthesis with Arenediazonium Salts: Cross-Coupling, CH-Arylation and Annulation Reactions
Felpin, F.-X.; Sengupta, S.
Chem. Soc. Rev. 2019, 48, 1150-1193. DOI
101- An Autonomous Self-Optimizing Flow Reactor for the Synthesis of Natural Product Carpanone
Cortés-Borda, D.; Wimmer, E.; Gouilleux, B.; Barré, E.; Oger, N.; Goulamaly, L.; Peault, L.; Charrier, B.; Truchet, C.; Giraudeau, P.; Rodriguez-Zubiri, M.; Le Grognec, E.; Felpin, F.-X.
J. Org. Chem. 2018, 83, 14286-14299. DOI
100- Hydrophobic Covalent Patterns on Cellulose Paper through Photothiol-X Ligations
Bretel, G.; Nongbe, M. C.; Le Grognec, E.; Felpin, F.-X.
ACS Omega 2018, 3, 9155-9159. DOI
99- Flow reactors integrated with in-line monitoring using benchtop NMR spectroscopy
Giraudeau, P.; Felpin, F.-X.
React. Chem. Eng. 2018, 3, 399-413. DOI
98- Cellulose paper grafted with polyamines as powerful adsorbent for heavy metals
Nongbe, M. C.; Bretel, G.; Ekou, L.; Ekou, T.; Yao, B. K.; Le Grognec, E.; Felpin, F.-X.
Cellulose, 2018, 25, 4043-4055, DOI
97- Cellulose Paper Azide as a Molecular Platform for Versatile Click Ligations – Application to the Preparation of Hydrophobic Paper Surface
Nongbe, M. C.; Bretel, G.; Ekou, L.; Ekou, T.; Robitzer, M.; Le Grognec, E.; Felpin, F.-X.
Cellulose, 2018, 25, 1395-1411, DOI
96 – Ultra-Fast Suzuki and Heck Reactions for the Synthesis of Styrenes and Stilbenes Using Arenediazonium Salts as Super-Electrophiles
Trusova, M. E.; Rodriguez-Zubiri, M.; Kutonova, K. V.; Jung, N.; Bräse, S.; Felpin, F.-X.; Postnikov, P. S.
Org. Chem. Front., 2018, 5, 41-45. DOI
95 – Photoresponsive cellulose paper as a molecular printboard for covalent printing
Rull-Barrull, J.; d’Halluin, M.; Le Grognec, E.; Felpin, F.-X.
J. Mat. Chem. C. 2017, 5, 5154-5162, DOI
94 – Oxidative Neutralization of Mustard-Gas Simulants in an On-Board Flow Device with In-Line NMR Monitoring
Picard, B.; Gouilleux, B.; Lebleu, T.; Maddaluno, J.; Chataigner, I.; Penhoat, M.; Felpin, F.-X.; Giraudeau, P.; Legros, J.
Angew. Chem. Int. Ed. 2017, 56, 7568-7572, DOI
93 – Biodiesel production from palm oil using sulfonated graphene catalyst
Nongbe, M. C.; Ekou, T.; Ekou, L.; Benjamain, Y. K. ; Le Grognec, E. ; Felpin, F.-X.
Renew. Energy 2017, 106, 135-141, DOI
92 – Chemically modified cellulose filter paper for heavy metal remediation in water
d’Halluin, M.; Rull-Barrull, J.; Le Grognec, E.; Felpin, F.-X.
ACS Sustainable Chem. Eng. 2017, 5, 1965-1973, DOI
91 – A highly selective colorimetric and fluorescent chemosensor for Cr2+ in aqueous solution
Rull-Barrull, J.; d’Halluin, M.; Le Grognec, E.; Felpin, F.-X.
Tetrahedron Lett. 2017, 58, 505-508, DOI
90 – Copper(II)-phenanthroline hybrid material as efficient catalyst for the multicomponent synthesis of 1,2,3-triazoles via sequential azide formation/1,3-dipolar cycloaddition
Nunes, A.; Djakovitch, L.; Khrouz, L.; Felpin, F.-X.; Dufaud, V.
J. Mol. Cat. A. 2017, 437, 151-157, DOI
89 – Optimizing the Heck-Matsuda Reaction in Flow with a Constraint-Adapted Direct Search Algorithm
Cortés-Borda, D.; Kutonova, K.; Jamet, C.; Trusova, M.; Zammattio, F.; Truchet, C.; Rodriguez-Zubiri, M.; Felpin, F.-X.
Org. Process. Res. Dev. 2016, 20, 1979-1987, DOI
88 – Graphene catalyzed transacetalisation under acid-free conditions
Nongbe, M. C.; Oger, N.; Ekou, T.; Ekou, L.; Benjamain, Y. K. ; Le Grognec, E. ; Felpin, F.-X.
Tetrahedron Lett. 2016, 57, 4637-4639, DOI
87 – Harnessing the dual properties of thiol-grafted cellulose paper for click reactions: powerful reducing agent and adsorbent for Cu
Rull-Barrull, J.; d’Halluin, M.; Le Grognec, E.; Felpin, F.-X.
Angew. Chem. Int. Ed. 2016, 55, 13549-13552, DOI
86 – The promoting effect of pyridine ligands in the Pd-catalysed Heck-Matsuda reaction
Khodja, W.; Leclair, A.; Zammattio, F.; Rull-Barrull, J.; Kutonova, K. V.; Trusova, M. E.; Felpin, F.-X.; Rodriguez-Zubiri, M.
New J. Chem. 2016, 40, 8855-8862, DOI
85 – Writing and Erasing Hidden Optical Information on Covalently Modified Cellulose Paper
d’Halluin, M.; Rull-Barrull, J.; Le Grognec, E.; Jacquemin, D.; Felpin, F.-X
Chem. Commun. 2016, 52, 7672-7675, DOI
84 – A paper-based biomimetic device for the reduction of Cu(II) to Cu(I) – Application to the sensing of Cu(II)
Rull-Barrull, J.; d’Halluin, M.; Le Grognec, E.; Felpin, F.-X.
Chem. Commun. 2016, 52, 6569-6572, DOI